Extracellular matrix regulation of autophagy
نویسندگان
چکیده
منابع مشابه
Induction of autophagy during extracellular matrix detachment promotes cell survival.
Autophagy has been proposed to promote cell death during lumen formation in three-dimensional mammary epithelial acini because numerous autophagic vacuoles are observed in the dying central cells during morphogenesis. Because these central cells die due to extracellular matrix (ECM) deprivation (anoikis), we have directly interrogated how matrix detachment regulates autophagy. Detachment induce...
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ژورنال
عنوان ژورنال: Current Opinion in Cell Biology
سال: 2008
ISSN: 0955-0674
DOI: 10.1016/j.ceb.2008.05.002